Published 04 Jul, 2022

Significance of the indicator


In the 2022 Cancer data in Australia (CdiA) report, two sets of mortality data were published. One was sourced from the National Mortality Database (NMD) having actual data from 1971 to 2022 and projections to 2024 and the other was derived from the Australian Cancer Database (ACD) comprising actual data from 2017 to 2020 with projections to 2024.1,2 Prior to 2022, only the NMD was used to report cancer mortality. While data presented in figures were extracted from the NMD, in the narratives, mortality rates projected in 2024 are discussed using both data from NMD and ACD for those cancers with recommendations and preference for use of the ACD in the AIHW’s interim recommendations (e.g., colon cancer, liver cancer, oesophageal cancer, head and neck cancer including lips, ovarian cancer and rectal cancer).3 International data were taken from the latest GLOBOCAN estimates produced by the International Agency for Research on Cancer (IARC) and disseminated as Cancer Today on the Global Cancer Observatory.4,5
 

Summary


Cancer mortality in Australia is increasing overall.

From 1971 to 2024, numbers of deaths for all cancers combined increased from 18,346 to an estimated 52,671 deaths per year.

Age-standardized mortality rates are decreasing for most cancer types.

Between 1971 and 2024, age-standardized mortality rates decreased for all cancers combined from 252.8 to 194.0 deaths estimated per 100,000 persons, and for most cancer types, except for increasing trends for cancers of the brain, liver, pancreas and melanoma of the skin, and with marginal changes for rectum, non-Hodgkin lymphoma and unknown primary site. 

Age-standardized mortality rates are higher in males than females for all cancers combined.

In 2024, age-standardized mortality rates estimated in males and female were 239.5 and 157.4 deaths per 100,000, respectively.

Cancer mortality rates for all cancers combined for people aged in their 30s and 40s are decreasing.

Age-standardized mortality rates in their thirties and forties decreased steadily from 26.5 and 89.7 to 12.4 and 36.9 deaths per 100,000 persons, respectively. 

Australia's cancer mortality rate is in the lower end range among 15 comparison countries.

The projected age-standardized cancer mortality rate per 100,000 in Australia was the fourth lowest (83.6 deaths per 100,000) among the comparison countries. 
 

    Charts
    • Notes
      Data sourced from Australian Institute of Health and Welfare 2021. Australian Cancer Incidence and Mortality (ACIM) books. Canberra: AIHW. [Accessed February 2022]. https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/data
      Table caption
      Annual mortality, by sex, 1968 to 2019
    • Notes
      Data sourced from Australian Institute of Health and Welfare 2021. Australian Cancer Incidence and Mortality (ACIM) books. Canberra: AIHW. [Accessed February 2022]. https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/data
      Table caption
      Age-standardised mortality rate, by sex, 1968 to 2019
    • Notes
      Data sourced from Australian Institute of Health and Welfare 2021. Australian Cancer Incidence and Mortality (ACIM) books. Canberra: AIHW. [Accessed February 2022]. https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/data
      Table caption
      Age-specific mortality rate, by sex, 2019
    • Notes
      Data sourced from Australian Institute of Health and Welfare 2021. Australian Cancer Incidence and Mortality (ACIM) books. Canberra: AIHW. [Accessed February 2022]. https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/data
      Table caption
      Age-specific mortality, by age group and sex, 1968 to 2019
    • Notes
      • Data sourced from AIHW
      • Data shown for 'Indigenous', 'Non-Indigenous', 'Not stated' and 'Total' are for NSW, Qld, WA, SA and NT only.
      • 'Total' age group includes counts of deaths with unknown age. However, deaths with unknown age were excluded from calculations of rates.
      • Rates are calculated using the sum of estimated resident populations at 30 June for 2015–2019. The rates given for age groups are age-specific rates per 100,000. The rates given for 'Total' are age-standardised rates per 100,000, standardised against the 2001 Australian Standard Population.
      • Rates are not published where there were fewer than 5 people.
      Table caption
      Age-standardised mortality, by Indigenous status, 2015-2019
    • Notes
      • Remoteness was classified according to the Australian Statistical Geography Standard (ASGS) Remoteness Areas.
      • The rates shown are age-standardised rates, standardised against the 2001 Australian Standard Population.
      Table caption
      Age-standardised mortality, by sex and remoteness, 2015–2019
    • Notes
      • SES area is classified according to the SEIFA quintile. Disaggregation by SEIFA quintile is based on Statistical Area Level 2 (SA2).
      • The rates shown are age-standardised rates, standardised against the 2001 Australian Standard Population.
      Table caption
      Age-standardised mortality, by sex and SES area, 2015–2019
    • Notes
      • Data sourced from International Agency for Research on Cancer GLOBOCAN 2019 database.
      • Rates are age-standardised to the WHO world standard population.
      Table caption
      Age standardised mortality estimates by country and cancer type

    Cancer mortality data generally refer to the number of deaths in a calendar year for which the underlying cause is cancer. This can be expressed as absolute numbers of deaths or as rates per 100,000 people. Mortality rates are often age-standardized to enable comparisons across different populations with different age profiles, noting that the likelihood of death from cancer generally increases with age.1 Age-specific rates are used to compare cancer mortality between different age groups. 

    Age-standardized and age-specific data are released each year by the Australian Institute of Health and Welfare (AIHW) for individual cancer types and cancer groupings. These cancer types and groupings are classified using ICD-10 coding.1 

    International cancer mortality data are available through the Global Cancer Observatory (GCO) project; these data are age-standardized to the overall age structure of the world population.4,5 International comparisons are made using this indicator for 15 economically developed countries across five continents. These countries are Australia, Canada, Chile, France (metropolitan), Germany, Ireland, Japan, the Republic of Korea, New Zealand, Singapore, Sweden, the Netherlands, the United Kingdom, United States of America (USA) and Uruguay.

    In 2024, the highest projected age-standardized mortality rates per 100,000 persons were for cancers of the lung (32.8), colon/rectum (19.3), pancreas (14.4), prostate (14.4), and breast (12.2). Age-standardized mortality rates were higher in males than females for all cancer types, except breast cancer.

    All cancers combined (ICD-10 codes C00–C97, D45, D46, D47.1, D47.3–D47.5)

    In 2024, it is estimated that there would be 52,671 deaths (29,531 males and 23,140 females equating with the age-standardized mortality rate (to the 2024 Australian population distribution) of 194.0 deaths per 100,000 persons (239.5 for males and 157.4 for females). 

    Age-specific mortality rates generally increase with age, with the highest rate in the age group of 90 years and older (2,829 deaths per 100,000 persons). This pattern applied to both males and females. 

    International comparisons 

    In 2022, the projected age-standardized mortality rate for Australian people for all cancers combined excluding non-melanoma skin cancer was estimated to be the fourth lowest (83.6 deaths per 100,000) among the selected comparison countries (for this international comparison, data are for ICD-10 codes C00–C97/C44). This is in contrast to Australia’s cancer incidence rate which typifies the higher rates generally seen in high-income countries plus high rates of sun-related cancers. This pattern was similarly the 3rd lowest in Australian males and females, respectively.

    Bladder cancer (ICD-10 code C67)

    In 2024, bladder cancer was estimated to be the fourteen most common cause of cancer death in Australia.6 There were an estimated 1,121 deaths (791 males and 330 females) equating with an age-standardized mortality rate of 4.1 deaths per 100,000 persons (6.7 for males and 2.1 for females per 100,000). Age-specific mortality rates generally increase with age, especially from ages 45-49 years, with the highest rate for ages 90 years and over at 130.6 deaths per 100,000 persons (estimated in 2024). This pattern was the same in males and females.

    International comparisons 

    In 2022, the projected age-standardized mortality rate for bladder cancer in Australian at 1.8 deaths per 100,000 persons ranked the 4th lowest, compared with the highest rate estimated for France of 3.4 deaths per 100,000 persons, among comparison countries. This rate ranked the 4th lowest in both males and females in Australia.

    Brain cancer (ICD-10 code C71)

    In 2024, brain cancer was estimated to be the ninth most common cause of cancer death in Australia.6 It corresponds with 1,606 deaths (975 males and 631 females) and an age-standardized mortality rate of 5.9 deaths per 100,000 persons (7.5 for males and 4.4 for females per 100,000).

    Age-specific mortality rates for brain cancer generally increase with age, especially from ages 35-39 years. The highest rate was in age group of 85-89 years at 26 cases per 100,000 persons. This pattern was the same in females. But in males, the highest rate was in ages 80-84 years at 32.4 cases per 100,000 men.

    International comparisons 

    International data are available for brain and central nervous system cancers combined (ICD-10 codes C70–72). In 2022, the projected age-standardized mortality rate for brain and central nervous system cancers in Australians was at the higher middle part of the range for the comparison countries (6th), with an estimated rate of 3.7 deaths per 100,000 persons. The highest estimated rate of 4.3 deaths per 100,000 persons was for Sweden, and the lowest was for Japan at 1.2 deaths per 100,000 persons. In both males and females, the rank for Australia was in the middle of the range (4.6 deaths and 2.9 per 100,000 in males and females, respectively). 

    See more details in reference 7.7

    Breast cancer in females (ICD-10 code C50)

    In 2024, breast cancer was estimated to be the fifth most common cause of cancer death overall and the 2nd most common in females in Australia.6 This corresponds with 3,272 deaths in females with an age-standardized mortality rate per 100,000 women of 22.4 deaths.

    Age-specific mortality rates generally increased with ages from 30-34 years, being highest for ages 90 years or over at 285.7 deaths per 100,000 females.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for breast cancer in Australian females ranked the sixth-lowest among selected developed countries at 12.3 deaths per 100,000 females. The highest estimated rate of deaths per 100.000 females was for Uruguay at 21.6 per 100,000, whereas the lowest was for Korea at 5.8 per 100,000.

    Cervical cancer (ICD-10 code C53)

    In 2024, cervical cancer was estimated to be the 20th most common cause of cancer death in females in Australia. There were an estimated 243 deaths attributed to cervical cancer in Australia with an age-standardized mortality rate at 1.7 per 100,000 females. 

    Age-specific mortality rates generally increased with ages from 35-39 years and were the highest for ages 90 years or over at 7.1 deaths per 100,000 females.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for cervical cancer in Australian females was the lowest among the comparison countries at 1.4 deaths per 100,000 females, which was quite similar to New Zealand (1.5 per 100,000). The highest mortality rate was recorded in Chile and Uruguay at 5.2 deaths per 100,000 females.

    Colorectal cancer (ICD-10 codes C18–C20, C26.0)

    In 2024, colorectal cancer was estimated to be the second most common cause of cancer death in Australia.6 There were an estimated 5,239 deaths (2,730 males and 2,509 females) giving an age-standardized mortality rate of 19.3 deaths per 100,000 persons (22.2 for males and 16.8 for females per 100,000). 

    Age-specific mortality rates for colorectal cancer generally increased with age, notably from ages 30-34 years. The highest rate was in the age group of 90 years and over at 392.3 deaths per 100,000 persons. This pattern was similar in males and females (429.7 deaths in ages 90+ years in males and 371.4 in females of that age respectively, per 100.000).
    International comparisons 

    International data are available for colorectal and anal cancers combined (ICD-10 codes C18–21). In 2022, the estimated age-standardized mortality rate for colorectal and anal cancers combined in The Australian death rate was the 3rd lowest among selected countries, alongside Korea with 8.6 deaths per 100,000 persons. United States had the lowest rate and Singapore the highest (7.9 and 16.7 deaths per 100,000 respectively). This rate ranked the 2nd lowest in males (10.4 deaths per 100,000) and the 3rd lowest in females (7.0 deaths per 100,000) in Australia.
    See more details for colorectal cancer in reference 8.8

    Colon cancer (ICD-10 code C18)

    As in the Australian Cancer Database (ACD), in 2024, there were an estimated 3,425 deaths from colon cancer in Australia (1,672 males and 1,753 females). The age-standardized mortality rate was an estimated 12.6 deaths per 100,000 persons (13.6 for males and 11.7 for females per 100,000). (Note: the ACD was recommended in reporting mortality rates for colon cancer).1,3
    As in NMD, in 2024, there were an estimated 1,237 deaths from colon cancer in Australia (575 males and 662 females). The age-standardized mortality rate was estimated at 4.6 deaths per 100,000 persons (4.8 for males and 4.4 for females per 100,000). 

    Age-specific mortality rates increased with age, notably from ages 35-39 years. The highest rates were in the age group of 90 years and over at 124.7 and 242.0 deaths per 100,000 persons, as recorded in the NMD and ACD, respectively. This pattern was the same in males and females in both the NMD and ACD data (117.9 and 250.7 deaths in ages 90+ years in females and 136.8 and 226.3 in males per 100,000), respectively).

    International comparisons

    These data were not available for C18 as such.

    See data caveat for colon cancer reporting. 

    Rectal cancer (including rectosigmoid junction) (ICD-10 codes C19–C20)

    As in the ACD, in 2024, it is estimated that about 1,686 deaths (1,062 males and 624 females) occurred with an age-standardized mortality rate of 6.2 deaths per 100,000 persons (8.5 for males and 4.3 for females per 100,000). Age-specific mortality rates increase with age, notably from ages 30-34 years. The highest rate was in the age group of 90 years and over at 89.4 deaths per 100,000 persons. This pattern was the same in males and females (130.4 deaths in ages 90+ years in males and 66.4 in females per 100,000, respectively). (Note: the ACD was recommended in reporting mortality rate for rectal cancer).1,3

    As in NMD data, in 2024, it is estimated that there were about 3,051 deaths (1,709 males and 1,342 females) with an age-standardized mortality rate of 11.2 deaths per 100,000 persons (13.7 for males and 9.1 for females per 100,000). Age-specific mortality rates increase with age, notably from ages 30-34 years. The highest rate was in the age group of 90 years and over at 138.9 deaths per 100,000 persons. This pattern was the same in males and females (159.8 deaths in ages 90+ years in males and 127.1 at this age in females per 100,000).

    International comparisons 

    These data were not available for C19-C20.

    See data caveat for rectal cancer

    Head and neck cancer (including lip; ICD-10 codes C00-C14, C30–C32)

    In 2024, it is estimated that there will be about 1,412 deaths from these cancers (1,013 males and 399 females) with an age-standardized mortality rate using the Australian Cancer Database (ACD) at 5.2 deaths per 100,000 persons (8.0 for males and 2.7 for females per 100,000) (Note: the ACD was recommended for reporting mortality rate for head and neck cancer including lip).1,3

    The age-standardized mortality rate as per the National Mortality Database (NMD) was 4.9 deaths per 100,000 persons (7.6 for males and 2.5 for females per 100,000). It corresponded with 1,318 deaths from these cancers (958 males and 360 females). The rates in males tripled that in females.

    Age-specific mortality rates increase with age, notably from ages 45-49 years. The highest rate was in the age group of 90 years and over at 47.7 and 41.7 deaths per 100,000 persons using the NMD and ACD, respectively. This pattern was the same in males (80.6 and 65.2 deaths in ages 90+ years using the NMD and ACD, respectively) and females (29.3 and 28.6 in females per 100,000, again using the NMD and ACD, respectively).

    International comparisons 

    Comparable international data are not available for head and neck cancers.

    Liver cancer (ICD-10 code C22)

    In 2024, liver cancer was estimated to be the sixth most common cause of cancer death in Australia with 2,041 deaths (1,453 males and 588 females).6 The age-standardized mortality rate was 7.5 per 100,000 persons (10.8 for males and 4.3 for females per 100,000) (Note: using the Australian Cancer Database (ACD) as recommended).1,3

    Using the National Mortality Database (NMD), there were an estimated 2,595 deaths (1,689 males and 906 females) with an age-standardized mortality rate of 9.6 deaths per 100,000 persons (13.3 for males and 6.2 for females). The rates in males were double that in females. 

    Age-specific mortality rates increased with age, notably from ages 40-44 years. The highest rate was in the age group of 85-89 years at 73.8 and 50.0 deaths per 100,000 persons (as per NMD and ACD, respectively). The pattern was the same in male but in females, the highest rate was in ages 90 years and over at 63.6 and 39.3 deaths per 100,000 females (as per NMD and ACD, respectively).

    International comparisons 

    International data were available for cancers of the liver and intrahepatic bile ducts. In 2022, the estimated age-standardized mortality rate for liver cancer in Australia was the 4th highest among the selected comparison countries, with 4.8 deaths per 100,000 persons. The highest rate was in Singapore at 11.0 deaths per 100,000 persons, respectively. This ranking was similar in males whereas the Australian rate was middle-ranking in females.

    Lung cancer (ICD-10 codes C33–C34)

    In 2024, lung cancer was the most common cause of cancer death in Australia.6 It is estimated that there would be about 8,918 deaths (4,909 males and 4,009 females) with an age-standardized mortality rate at 32.8 deaths per 100,000 persons (39.1 for males and 27.7 for females per 100,000). 

    The mortality rate for lung cancer increases with age, particularly from ages 45-49 years. The highest rate was for ages 85-89 years at 261.1 deaths per 100,000. The highest rates were for ages 85-89 years in females at 199.5 deaths and for ages of 90 years and over in males at 383.6 deaths per 100,000.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for lung cancer in Australia was the fourth-lowest among the 15 selected developed countries, with 15.6 deaths per 100,000 persons. The highest rate per 100,000 persons was for Uruguay at 25.4 deaths while the lowest was for Chile at 11.3 deaths. The Australian rate ranked the 3rd lowest in males and the 5th lowest in females.

    Melanoma of the skin (ICD-10 code C43)

    In 2024, melanoma of the skin was the 11th most common cause of cancer death in Australia.6 It is estimated that there would be about 1,340 deaths (892 males and 448 females) with an age-standardized mortality rate of 4.9 deaths per 100,000 persons (7.3 for males and 3.0 for females per 100,000). The rate in males was more than double that in females. 

    The mortality rate for melanoma of the skin increased with age, notably from ages 35-39 years. The highest rates were for ages 90 years and over at 86.6 deaths per 100,000 persons. This pattern was similar in males and females with peak rates of 147.1 and 52.9 deaths per 100,000, respectively.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for melanoma of the skin for Australia (2.2 deaths per 100,000 persons) was the 2nd highest in the world after New Zealand (3.9 deaths per 100,000 persons). This pattern was similar in males and females.

    Non-Hodgkin lymphoma (ICD-10 codes C82–C86)

    In 2024, non-Hodgkin lymphoma was the eighth most common cause of cancer death in Australia.6 It is estimated that in 2024 there would be 1,795 deaths (1,040 males and 755 females) with an age-standardized mortality rate at 6.6 deaths per 100,000 persons (8.4 for males and 5.1 for females per 100,000). Age-specific mortality rates increase with age, particularly from the age group of 60–64 years. The highest rates were in ages 90 years and over at 101.7 deaths per 100,000 persons. This pattern was similar in males and females at 131.7 and 85.0 deaths per 100,000, respectively.

    International comparisons 

    International data are available for non-Hodgkin lymphoma (ICD-10 codes C82–86 and C88). In 2022, the estimated age-standardized mortality rate for non-Hodgkin lymphoma in Australia was in the middle part of the range of comparison countries with 2.8 deaths per 100,000 persons. The pattern was similar in males and females.

    Oesophageal cancer (ICD-10 code C15)

    In 2024, oesophageal cancer was the 13th most common cause of cancer death in Australia.6 Estimates from ACD data are that in 2024 there would be about 1,193 deaths (884 males and 309 females) corresponding with an age-standardized mortality rate of 4.4 deaths per 100,000 persons (7.0 for males and 2.1 for females per 100,000). (Note: the ACD was recommended to be used in this report for oesophageal cancer mortality).

    As in the NMD, there would be about 1,439 deaths (1,079 males and 360 females) giving an age-standardized mortality rate of 5.3 deaths per 100,000 persons (8.5 for males and 2.5 for females per 100,000) in 2024. The rates in males were more than triple that in females. 

    Age-specific mortality rates increased with age. The highest rates per 100,000 persons were for ages 90 and over as per NMD at 46.7 deaths and for ages 85-89 years as per ACD at 35.4 deaths.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for oesophageal cancer for Australia ranked 7th among the 15 comparison countries at 2.7 deaths per 100,000 persons. In Australian males, this rate was in the lower middle part of the range whereas it was in the middle part in females.

    Ovarian cancer (ICD-10 code C56)/Ovarian and serious carcinomas of the fallopian tube (C56 (all histology types) and C57.0, C57.8 (with histology types 8441, 8460, 8461))

    As per the ACD, it is estimated that in 2024 there would be about 1,067 deaths attributed to ovarian cancer and serous carcinomas of the fallopian tube, giving an age-standardized mortality rate of 7.4 deaths per 100,000 females. The mortality rate for ovarian cancer increases with age. The highest rate applied at ages 80-84 years at 55.3 deaths per 100,000 females.  (Note: the ACD was recommended to be used to report mortality in ovarian cancer).

    As per the NMD, it is estimated that in 2024 there would be about 1,054 deaths attributed to ovarian cancer, giving an age-standardized mortality rate of 7.3 deaths per 100,000 females. The mortality rate for ovarian cancer increased with age. The highest rate applied to ages 85-89 years at 54.0 deaths per 100,000 females.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for ovarian cancer in Australian females was the fifth lowest (3.9 deaths per 100,000) among the 15 comparison countries. The lowest rate was for Korea at 2.6 deaths per 100,000 females.

    See further details in reference 9.9

    Pancreatic cancer (ICD-10 code C25)

    In 2024, pancreatic cancer was estimated to have been the third most common cause of cancer death in 20246 when there would have been about 3,902 deaths (2,027 males and 1,875 females), giving an age-standardized mortality rate of 14.4 deaths per 100,000 persons (16.1 for males and 12.8 for females per 100,000). 

    Age-specific mortality rates increased with age, with the highest rate applying for ages 85-89 years at 130.7 deaths per 100,000 persons. This pattern was the same in females with peak at 125.8. The highest rate in males was in ages 90 years and over at 144.5 deaths per 100,000.
    International comparisons 

    In 2022, the estimated age-standardized mortality rate for pancreatic cancer in Australia was the 4th lowest among the selected comparison countries alongside Korea at 5.9 deaths per 100,000. This pattern was similar in males (5th lowest) and females (4thlowest). Uruguay had the highest rate at 9.4 deaths per 100,000 persons among the comparison countries.

    See further details in reference 10.10

    Prostate cancer (ICD-10 code C61)

    In 2024, prostate cancer was the fourth most common cause of cancer death overall and the second most common in males in Australia.6 It is estimated that there would be 3,901 deaths, giving an age-standardized mortality rate of 33.1 deaths per 100,000 males. 

    The mortality rate for prostate cancer increases with age from ages 50-54 years, being highest at ages of 90 years and over at 1,056.3 deaths per 100,000 males.

    International comparisons 

    In 2022, the estimated age-standardized mortality rate for prostate cancer in Australian males was the 8th among selected comparison countries, with 10.8 deaths per 100,000 males. Uruguay had the highest rate per 100,000 males at 17.8 deaths while the lowest rates were in Korea and Japan at 4.4 deaths per 100,000.

    See further details in reference 11.11

    Unknown primary site cancer (ICD-10 codes C77–C80, C97)

    In 2024, cancer of unknown primary site was the seventh most common cause of cancer death in Australia,6 with 1,872 deaths (996 males and 876 females), giving an estimated age-standardized mortality rate of 6.9 deaths per 100,000 persons (8.2 for males and 5.8 for females per 100.000) using ACD data.

    As in NMD, there were an estimated 2,897 deaths (1,607 males and 1,290 females), corresponding with an age-standardized mortality rate of 10.7 deaths per 100,000 persons (13.2 for males and 8.6 for females per 100.000). 

    Age-specific mortality rates increased with age. The highest rate was in the age group of 90 years and over at 223.6 and 173.2 deaths per 100,000 persons using NMD and ACD data, respectively. This pattern was the same in males (285.2 and 190.5 deaths in ages 90+ years using the NMD and ACD, respectively) and females (189.3 and 163.6 in females per 100,000, again using the NMD and ACD, respectively).

    International comparisons 

    Comparable international data are not available for cancers of unknown primary site.

    Uterine cancer (ICD-10 codes C54–C55)

    In 2024, uterine cancer was the 8th most common cause of cancer death in females in Australia.6 There were an estimated 693 deaths, giving an age-standardized mortality rate of 4.8 deaths per 100,000.  Age-specific mortality rates generally increased with age from age 40-44 years, reaching a peak at ages 85-89 years of 34.2 deaths per 100,000.

    International comparisons 

    International data estimates are available for uterine cancer for the ICD-10 code C54 only. In 2022, the estimated age-standardized mortality rate for uterine cancer was the fifth-lowest (same as for Sweden) among comparison countries, with 2.2 deaths per 100,000 females. The highest rate was for Singapore at 3.8 deaths per 100,000 females.

    Cancer mortality refers to the number of deaths occurring during a specified time period (usually one year) for which the underlying cause of death is cancer.

    The major source of the cancer mortality data presented here was the National Mortality Database (NMD), which is compiled by the AIHW from data provided by state and territory Registries of Births, Deaths and Marriages, and the National Coronial Information System, and as coded by the Australian Bureau of Statistics (ABS), for deaths from 1964 to 2022. In this 2022 Cancer data in the Australia (CdiA) report, deaths registered in 2019 and earlier are based on the final version of cause of death data, whereas deaths registered in 2020, 2021 and 2022 are based on revised and preliminary versions and are subject to further revision by the ABS.1,12

    At the time of the 2022 release of the CdiA, two sets of mortality data were published, i.e.: the National Mortality Database (NMD) and the Australian Cancer Database (ACD). The AIHW provided a recommendation on which data source should be used for cancers reported in the CdiA.1,3 AIHW’s cancer mortality investigations are in a preliminary phase. Given that the preliminary findings indicated that the NMD may not be as appropriate for reporting mortality for certain cancers, the 2022 release of the CdiA mortality data also included ACD mortality data (Note: mortality estimates from the Australian Cancer Database for 2021-2024 are based on 2011-2020 data). The AIHW recommended using mortality data from the ACD when users focused solely on cancer mortality for the periods where ACD mortality data are available (currently 2007 to 2017).1,3 The December 2024 release of the Cancer data in Australia report includes the final elements of the cancer mortality project in which, for selected cancers, the cause of death as recorded by the Australian Cancer Database was compared with the cause of death as recorded by the National Mortality Database.1

    (Note: see more details in reference 1). 

    While the AIHW considers the ACD to generally provide more precise cancer mortality reporting, the ACD currently has a relatively limited time series and the NMD has more recent mortality data. The recency of NMD data means the 2018, 2019 and 2020 years are actual data within the NMD whereas only projected data are possible from the ACD for these years. The ACD and NMD mortality data for 2021 and 2022 are both projected. With its recency and extended time series, the NMD cancer statistics will offer stronger reporting for 2018 to 2022 where the NMD actual mortality statistics appears sufficiently representative for the selected cancer.1,3 

    Where the NMD is recommended for continued use for a particular cancer, the NMD data may be more comfortably used for pre-2007 cancer mortality reporting. While the NMD may have access to less information from which to identify underlying causes of death for cancer than the ACD, it has a longer historical time-series and is more up-to-date. At the time of releasing the CdiA, mortality data from the NMD, it was sufficiently complete for reporting up to 2020, while the ACD incidence data was sufficiently complete for reporting up to 2018 (with some estimation of late registrations) and ACD mortality data were complete up to 2017. It is possible that, like the 2018 incidence data, there may still be some outstanding mortality information that is yet to be provided to the ACD. Accordingly, the 2017 ACD may under-count mortality to some extent.1,3

    NMD data are derived from information recorded on death certificates. Therefore, the NMD does not include histology information nor have access to some of the additional information used to derive the ACD data, which enables cancer type to be more accurately assigned in the ACD in some cases.1,3

    Cancer is classified by the International Statistical Classification of Diseases and Related Health Problems Version 10 (ICD–10). This is a statistical classification, published by the World Health Organization, in which each morbid condition is assigned a unique code according to established criteria. The cancers in the ACD are coded using the 2nd revision of the 3rd edition of the International Classification of Diseases for Oncology (ICD-O-3.2). The ICD-O-3.2 codes can be mapped to the tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10).12 All cancers combined incorporate ICD-10 cancer codes C00–C96 with mortality also incorporating C97, D45 (polycythaemia), D46 (myelodysplastic syndromes), and D47.1, D47.3, D47.4 and D47.5 (myeloproliferative diseases) but excluding basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin. BCC and SCC, the most common skin cancers, are not notifiable diseases in Australia and are not reported in the Australian Cancer Database.12

    Projections - Estimating the mortality of cancer

    This method is the same as the incidence projections with the exceptions that the 10-year baseline for incidence is 2011–2020 while the baseline for mortality from the NMD is 2013–2022 and the baseline for mortality from the ACD is 2011–2020. The 2023–2024 mortality estimates from the National Mortality Database are projections based on 2013-2022 data.1,12

    Methodology12

    Age standardization

    Age-standardized mortality rates for the Australian population were age standardized to the 2001 Australian Standard Population and a separate series was available with standardization to the 2024 Australian population. Rates are expressed per 100,000 population.

    International data

    The Global Cancer Observatory (GCO) contains cancer incidence and mortality from cancer registries around the world. Various methodologies are applied to the GCO data that differ by country and data availability.4,5 Additional details on methodology and data availability can be found in reference 13.13 International mortality data are age-standardized to the World standard population, which generally gives appreciably lower rates than standardization to the Australian population due to differences in age weightings.1,12,13

    Data caveat

    For all cancers combined, the NMD is recommended for reporting based on the completeness of the data. Notably, a greater level of agreement is seen between the ACD and NMD data for all cancers combined as they are obtained from the same source (note: the NMD has added value with coded causes for all deaths).1,3

    For liver cancer mortality reporting, the ACD is recommended. The NMD provides the only source of longer-term national historical mortality reporting for this cancer. The general trend of ACD liver cancer mortality also supports the general trend of NMD liver cancer mortality.3 Even though the ACD is recommended, the NMD could be considered the best data source for the reporting of liver cancer mortality over time. In using these data, it would be important to note that the liver cancer mortality rates presented may be overstated (approximately 25% higher than the ACD between 2007 and 2017).1,3

    For ovarian cancer, mortality rates for cancers of the fallopian tube remain quite stable. Note: an exact comparison cannot be made because the NMD does not collect information about cancer histology. It is therefore not possible to isolate ovarian cancer deaths from those from serous carcinomas of the fallopian tube, such that all cancers of the fallopian tube are reported (not only serous carcinomas). Unlike incidence data, mortality was reported for ovarian cancer not ovarian cancer and serious carcinomas of the fallopian tubes.1,3,9

    For colorectal cancer, unlike the incidence data, the mortality data include the unspecified part of the intestinal tract (ICD-10 code: C26.0) in addition to the colorectal part (ICD-10 codes: C18–C20).1,5 Some likely reasons for the differences between colorectal cancer mortality data in the NMD and ACD include:1,3,8

    • The term bowel cancer is commonly used in Australia as an interchangeable term for colon cancer. The term bowel cancer is coded to C26.0 (Cancer of the intestinal tract, part unspecified) and colon cancer to C18.9 (colon, unspecified). For statistical analysis it is recommended that these two codes are combined.
    • C19 – the term colorectal cancer is often used on death certificates and the term is coded to C19 (cancer of the rectosigmoid junction).

    While the age-standardized rates for colon cancer were significantly higher in the ACD, these rates are higher in the NMD for rectal cancer.

    In future, colon or rectal cancer deaths will be unlikely to be published separately using the NMD due to the relatively large differences between the NMD and ACD. The information received on death certificates is unlikely to enable finer level reporting such as colon or rectal cancer from the NMD but it is suitable for reporting for the broader range of colorectal cancer.1,3,8

    Data sources 

    1. Australian Institute of Health and Welfare. Cancer data in Australia. Data. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/data
       
    2. Global Cancer Observatory: Cancer Today.  International Agency for Research on Cancer. Lyon, France. Accessed Dec 2024; https://gco.iarc.fr/today
       

    Activity in this area
     

    Data

    1. Australian Institute of Health and Welfare. Cancer data in Australia. Data. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/data
       
    2. Global Cancer Observatory: Cancer Today.  International Agency for Research on Cancer. Lyon, France. Accessed Dec 2024; https://gco.iarc.fr/today

    References
     

    1. Australian Institute of Health and Welfare 2024. Cancer data in Australia. Web report. Cat. no. CAN 122. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/about
       
    2. Australian Institute of Health and Welfare.  Cancer mortality by age visualisation. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-mortality-by-age-visualisation
       
    3. Australian Institute of Health and Welfare 2024. Cancer data commentary 8b. Interim guidelines – choosing which mortality data source to use (2024 update). Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-data-commentaries/interim-guidelines-choosing-which-mortality-data
       
    4. Global Cancer Observatory: Cancer Today.  International Agency for Research on Cancer. Lyon, France. Accessed Dec 2024; https://gco.iarc.fr/today
       
    5. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024 May-Jun;74(3):229-263
       
    6. Australian Institute of Health and Welfare 2022.  Cancer data in Australia. Cancer rankings data visualisation. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-rankings-data-visualisation
       
    7. Australian Institute of Health and Welfare 2024. Cancer data commentary 4. A different view of brain cancer rate changes over time. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-data-commentaries/a-different-view-of-brain-cancer-rate-changes-over
       
    8. Australian Institute of Health and Welfare 2024. Cancer data commentary 12. An overview of colorectal cancer in Australia. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-data-commentaries/an-overview-of-colorectal-cancer-in-australia
       
    9. Australian Institute of Health and Welfare 2024. Cancer data commentary 5. Improving the understanding of ovarian cancer statistics. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-data-commentaries/improving-the-understanding-of-ovarian-cancer-stat
       
    10. Australian Institute of Health and Welfare 2024. Cancer data commentary 3. How are pancreatic cancer rates changing? Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-data-commentaries/how-are-pancreatic-cancer-rates-changing
       
    11. Australian Institute of Health and Welfare 2024. Cancer data commentary 9. Prostate cancer – projection method changes, updated long-term prostate cancer incidence projections. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/cancer-data-commentaries/prostate-cancer-projection-method-changes-updated
       
    12. Australian Institute of Health and Welfare 2024. Cancer data in Australia. Methods. Accessed Dec 2024; https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/technical-notes/methods
       
    13. Global Cancer Observatory: Cancer Today.  International Agency for Research on Cancer. Lyon, France. Data & Methods. Accessed Dec 2024; https://gco.iarc.fr/today/data-sources-methods#title-inc
       

    Summary

    Cancer mortality in Australia is increasing overall

    From 1968 to 2019, cancer mortality in Australia increased from 17,032 deaths to 49,035 deaths per year.

    Cancer mortality rates are decreasing for most cancer types

    From 1968 to 2019, age-standardised mortality rates decreased for all cancers combined, and for most cancer types, with exceptions including brain, liver and rectal cancer, and lung cancer in females.

    Aboriginal and Torres Strait Islander peoples have higher mortality rates for some cancers

    Indigenous Australians experienced higher age-standardised mortality rates than non-Indigenous persons for cancers of the bladder, breast in females, cervix, head and neck, liver, lung, oesophagus, pancreas, uterus, and unknown primary site.

    Disparities in cancer mortality in remote areas

    In 2015–2019, the age-standardised mortality rate for all cancers combined was highest in Remote and Very Remote areas combined and lowest in Major Cities, (180.6 compared with 150.7 deaths per 100,000 persons).

    Disparities in cancer mortality in lower SES areas

    In 2015–2019, the age-standardised mortality rate for all cancers combined was highest in the lowest SES areas (SES1 quintile, 184.9 deaths per 100,000 persons compared with the highest SES area (SES 5 quintile, 130.2 deaths per 100,000 persons).

    Australia's cancer mortality rate is lower than the estimated global average

    The projected age-standardised cancer mortality rate in Australia was about 18% lower than the estimated global rate for 2020.