Relative survival by stage at diagnosis (female breast cancer)

Published

01 Apr, 2019

Introduction:

This measure comprises national data on relative survival by stage at diagnosis for invasive female breast cancer.

Stage at diagnosis indicates the extent to which a cancer has spread at diagnosis. It is an important prognostic factor for cancer outcomes. It also provides contextual information for interpreting cancer outcomes, including survival, at a population level.¹

Relative survival refers to the probability of being alive for a given amount of time after diagnosis, compared with survival of the general population. Observed survival refers to the overall proportion of people who are alive following a specified amount of time (e.g. 1 year, 3 years or 5 years) after diagnosis of cancer. In this report, ‘survival’ refers to relative survival unless otherwise stated. Examining survival by stage at diagnosis provides insights into how survival outcomes differ depending on extent of cancer spread at diagnosis.

To provide a better understanding of cancer stage at diagnosis at the population-level, Business Rules were developed to collect national data on Registry-derived stage (RD-stage) at diagnosis using data sources that are routinely accessible to all population-based cancer registries. RD-stage is defined for invasive tumours only. More information on the capture and distribution of RD-stage at diagnosis can be accessed through the following measures:

The following sections of this report present 1, 3 and 5-year relative survival by RD-stage at diagnosis (hereafter referred to as ‘stage’) for females diagnosed with breast cancer in 2011. Data on survival by stage at diagnosis for other cancer types can be accessed through the following measures:

More information about data sources, methods for collection, and guidance for interpreting the data can be found in the ‘About the Data’ tab.

Data

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Notes

• Data are sourced from the Australian Institute of Health and Welfare. More information about data sources can be found in the ‘About the Data’ tab.
• Error bars indicate 95% confidence intervals.
• Relative survival for Registry-Derived stage was calculated using the cohort method, using the period 2011–2016.
• Survival greater than 100% applies where the survival of people with cancer exceeds the survival of people in the general population of equivalent age and sex over an equivalent time period.
• Data for some categories that do not appear in the charts have been deliberately suppressed due to small numbers, confidentiality, and/or reliability concerns.
• Survival estimates for cases for which stage at diagnosis was 'unknown' have not been displayed in the chart as this category will be comprised of cases with varying stage at diagnosis. For females, the 1, 3, and 5-year relative survival rates were 89.5%, 76.4% and 65.0%, respectively

Relative survival for female breast cancer by stage at diagnosis, 2011
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Stage at diagnosis

Notes

• Data are sourced from the Australian Institute of Health and Welfare. More information about data sources can be found in the ‘About the Data’ tab.
• Error bars indicate 95% confidence intervals.
• Relative survival for Registry-Derived stage was calculated using the cohort method, using the period 2011–2016.
• Survival greater than 100% applies where the survival of people with cancer exceeds the survival of people in the general population of equivalent age and sex over an equivalent time period.
• Data for age-groups 0-39 years were combined due to small numbers.
• Data for some categories that do not appear in the charts have been deliberately suppressed due to small numbers, confidentiality, and/or reliability concerns.

Relative survival for female breast cancer by stage at diagnosis and age, 2011
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Relative survival

Notes

• Data are sourced from the Australian Institute of Health and Welfare. More information about data sources can be found in the ‘About the Data’ tab.
• Error bars indicate 95% confidence intervals.
• Relative survival for Registry-Derived stage was calculated using the cohort method, using the period 2011–2016.
• Survival greater than 100% applies where the survival of people with cancer exceeds the survival of people in the general population of equivalent age and sex over an equivalent time period.
• Data for age-groups 0-39 years were combined due to small numbers.
• Data for some categories that do not appear in the charts have been deliberately suppressed due to small numbers, confidentiality, and/or reliability concerns.

Relative survival for female breast cancer by stage at diagnosis and age, 2011
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Relative survival

Notes

• Data are sourced from the Australian Institute of Health and Welfare. More information about data sources can be found in the ‘About the Data’ tab.
• Error bars indicate 95% confidence intervals.
• Relative survival for Registry-Derived stage was calculated using the cohort method, using the period 2011–2016.
• Survival greater than 100% applies where the survival of people with cancer exceeds the survival of people in the general population of equivalent age and sex over an equivalent time period.
• Data for some categories that do not appear in the charts have been deliberately suppressed due to small numbers, confidentiality, and/or reliability concerns.

Relative survival for female breast cancer by stage at diagnosis for <50/50+ years age groups, 2011
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Observed survival

Notes

• Data are sourced from the Australian Institute of Health and Welfare. More information about data sources can be found in the ‘About the Data’ tab.
• Error bars indicate 95% confidence intervals.
• Observed survival for Registry-Derived stage was calculated using the cohort method, using the period 2011–2016. Observed survival estimates do not involve comparisons with the general population. More information on the differences between observed and relative survival estimates can be found in the ‘About the Data’ tab.
• Remoteness area of the patient's usual place of residence was defined using the ABS Australian Statistical Geography Standard (ASGS) remoteness structure classification, 2011.
• Data for some categories that do not appear in the charts have been deliberately suppressed due to small numbers, confidentiality, and/or reliability concerns.

Observed survival for female breast cancer by stage at diagnosis and remoteness, 2011
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Observed survival

Notes

• Data are sourced from the Australian Institute of Health and Welfare. More information about data sources can be found in the ‘About the Data’ tab.
• Error bars indicate 95% confidence intervals.
• Observed survival for Registry-Derived stage was calculated using the cohort method, using the period 2011–2016. Observed survival estimates do not involve comparisons with the general population. More information on the differences between observed and relative survival estimates can be found in the ‘About the Data’ tab.
• Socioeconomic group of the patient's usual place of residence defined using the ABS SEIFA Index of Relative Socioeconomic Disadvantage, 2011.
• Data for some categories that do not appear in the charts have been deliberately suppressed due to small numbers, confidentiality, and/or reliability concerns.

Observed survival for female breast cancer by stage at diagnosis and SES, 2011

About this measure

This measure presents national survival by stage at diagnosis data for female breast cancer in Australia using data sources that are routinely accessible to all cancer registries. To date, RD-stage has been collected for a single index year (2011) as this represented the most up-to-date cancer incidence data for which 5-year survival by stage could be reported up to 2016. In collaboration with Cancer Australia, the population-based cancer registries (PBCRs), and the Australasian Association of Cancer Registries (AACR), the Australian Institute of Health and Welfare (AIHW) has combined the newly collected information on RD-stage, cancer incidence from the Australian Cancer Database (ACD), and mortality from the National Death Index (NDI).

Prior to 2018 the lack of high quality national cancer staging data had been an identified gap in our data knowledge in Australia. As part of the Stage, Treatment and Recurrence (STaR) project, Cancer Australia has worked with PBCRs and AACR to develop nationally-standardised methodologies for collecting stage at diagnosis data. This work has initially focussed on the top five incident cancers (female breast cancer, colorectal, lung, prostate cancer, and melanoma) for population-level reporting purposes.

Cancer Australia supported the Cancer Council Victoria (CCV) in developing Business Rules for the collection of national cancer stage at diagnosis for invasive tumours based on the Tumour, Node, and Metastases (TNM) staging system as developed and maintained by the American Joint Committee on Cancer (AJCC, 7^th edition) in collaboration with the International Union for Cancer Control (UICC). The TNM Staging System is based on the extent of the tumour (T), the extent of spread to the lymph nodes (N), and the presence of metastasis (M). As each cancer type has its own classification system, letters and numbers do not always mean the same thing for every kind of cancer. Once the T, N, and M are determined, they are combined, and an overall stage of 0, I, II, III, IV is assigned.²

Using these Business Rules, all Australian PBCRs have derived RD-stage at diagnosis using data sources that are routinely accessible to all cancer registries. RD-stage at diagnosis is defined as the best estimate of summary TNM stage at diagnosis that can be derived nationally by Australian cancer registries from the data sources available to them. Its purpose will be for population-based analyses, not clinical applications.

RD-stage has the following values:

Stage 1 (equivalent to TNM stage I; Early stage)
Stage 2 (equivalent to TNM stage II; Early stage)
Stage 3 (equivalent to TNM stage III; Locally advanced)
Stage 4 (equivalent to TNM stage IV; Metastatic)
Stage unknown
Stage not applicable (including tumours with morphologies not eligible for TNM and tumours with no histological confirmation) – These have been excluded for the purpose of this analysis.

Upcoming releases for stage at diagnosis data:

Cancer Australia has also supported the development of a set of complementary Business Rules for deriving cancer stage at diagnosis for 16 paediatric (childhood) cancer types. Initial data on childhood cancer stage at diagnosis were released for the first time in Australia on the NCCI website in August 2018. These initial data are available in the following measures:

The initial data presented for childhood cancers are for the years 2006-2010. The collection of these data for the remaining period of 2011-2014 is still in progress and more detailed data for the entire period of 2006-2014 will be available when this is finalised in 2019.

Current status

Survival by stage at diagnosis indicates the probability of surviving for a specified time-period depending on the extent of the cancer (stage) at diagnosis. To assist in interpreting the data, some of the findings in the following sections are grouped into:

Early stage cancers (stage 1 and 2) – restricted to the local area of origin of the cancer;
Locally advanced cancers (stage 3) – cancers which have spread locally; and
Metastatic cancers (stage 4) – cancers which have spread to distant sites.

The stage at diagnosis for female breast cancer has been derived from data sources that are routinely accessible to all population-based cancer registries. These data are intended to be used for broad population-based analyses, and not to guide care of an individual.

The data showed that for female breast cancers diagnosed in 2011, a high proportion of cases were early stage cancers:

Early stage cancers (stage 1 and 2) accounted for around three quarters (77%) of incident cases.
- Stage 1 cancers accounted for 43% of cases (6,110 cases);
- Stage 2 cancers accounted for 35% of cases (4,936 cases).
Locally advanced cancers (stage 3) accounted for 12% of cases (1,721 cases).
Metastatic cancers (stage 4) accounted for 5% of cases (660 cases).
It was not possible to determine stage at diagnosis for 6% of cases (unknown stage; 788 cases).

More information on the distribution of stage at diagnosis can be accessed through the ‘Distribution of cancer stage’ measure.

Relative survival by RD-stage at diagnosis for female breast cancers diagnosed in 2011

Relative survival for all female breast cancers

Survival for females diagnosed with breast cancer in 2011 decreased with increasing time from diagnosis at:

98% at 1 year from diagnosis;
95% at 3 years from diagnosis;
91% at 5 years from diagnosis.

Although these data provide insights into survival for females diagnosed with breast cancer, it is also important to examine how survival differs by the extent to which a cancer has spread when first diagnosed.

Relative survival by RD-stage for all female breast cancers

Examining relative survival by stage at diagnosis showed that survival was high for females diagnosed with early stage breast cancers and survival remained high up to 5 years from diagnosis. Cancers diagnosed at stage 3 and 4 had progressively lower survival in subsequent years from diagnosis compared to early stage cancers. Survival by stage at diagnosis is examined in more detail in the following sections.

Relative survival for early stage breast cancers

For females diagnosed with early stage cancers (stage 1 and 2), survival remained high up to 5 years from diagnosis.

Survival for females diagnosed with:

Stage 1 cancers was 100% at 1, 3 and 5 years from diagnosis;

Stage 2 cancers decreased from 100% to 98% between 1 and 3 years from diagnosis. Survival decreased further to 95% at 5 years from diagnosis.

Relative survival for advanced breast cancers

Survival was lower for females diagnosed with advanced cancers, particularly for cancers diagnosed as metastatic (stage 4). Survival also decreased with increasing time from diagnosis for stage 3 and 4 cancers.

Survival for females diagnosed with:

Locally advanced cancers (stage 3) decreased from 98% to 88% between 1 and 3 years from diagnosis. Survival decreased further to 81% at 5 years from diagnosis;
Metastatic cancers (stage 4) decreased from 69% to 47% between 1 and 3 years from diagnosis. Survival decreased further to 32% at 5 years from diagnosis.

Relative survival by stage at diagnosis and age in 2011

Relative survival by age for female breast cancers

The analysis in the following section examines overall patterns in relative survival across age groups where there were sufficient numbers for reporting purposes. The overall trend showed a lower survival with increasing age for cancers diagnosed at stage 3 and 4. Guidance for interpreting the data can be found in the ‘About the Data’ tab.

For stage 1 cancers, survival was similar across all age groups at 1, 3 and 5 years from diagnosis (at least 98%).

For stage 2 cancers, survival was similar across all age groups at 1 year (at least 99%), 3 years (between 96% and 99%) and 5 years from diagnosis (between 90% and 97% for females in age groups less than 70 years).

For locally advanced cancers (stage 3):

Survival varied across all age groups at 1 year (between 89% and 100%), 3 years (between 68% and 95%) and 5 years from diagnosis (between 67% and 89%);

Survival generally decreased with increasing age for females:
- In age groups between 65 and 85 years and over from 91% to 68% at 3 years from diagnosis;
- In age groups between 65 and 84 years from 89% to 67% at 5 years from diagnosis.

For metastatic cancers (stage 4):

Survival varied across all age groups at 1 year (between 41% and 95%), 3 years (between 38% and 65% for females in age groups less than 80 years) and 5 years from diagnosis (between 30% and 49% for females in age groups between 45 and 74 years of age);
Survival also generally decreased with increasing age for females:
- Across all age groups from 95% to 41% at 1 year from diagnosis;
- In age groups between 40 and 79 years from 65% to 38% at 3 years from diagnosis.
Survival varied among females in age groups between 45 and 74 years, ranging between 30% and 49% at 5 years from diagnosis.

Relative survival by age (<50 years and ≥50 years age groups)

This section examines patterns in relative survival for females aged 50 years and over compared to females aged less than 50 years. A similar proportion of cases (between 4% and 7% of cancers) were not able to be staged for both age groups.

Females aged 50 years and over when diagnosed:
- Accounted for 77% of cases eligible for staging;
- Had a high proportion of cases (78%) diagnosed at an early stage (stage 1, 45%; stage 2, 33%) whilst more advanced cancers combined accounted for 16% of cases (stage 3, 11%; stage 4, 5%).
Females aged less than 50 years when diagnosed:
- Accounted for a low proportion of cases overall (23%);
- Had a high proportion cases (77%) diagnosed at an early stage (stage 1, 37%; stage 2, 40%) whilst more advanced cancers accounted for 19% of cases (stage 3, 15%; stage 4, 4%).

For early stage cancers (stage 1 and 2), survival by stage at diagnosis was similar for both age groups at 1, 3 and 5 years from diagnosis (between 94% and 100%).

For locally advanced cancers (stage 3):

Females aged 50 years and over had similar survival to those aged less than 50 years at 1 year from diagnosis (98% compared to 99%);
Females aged 50 years and over had lower survival compared to those aged less than 50 years:
- 86% compared to 93% at 3 years from diagnosis;
- 78% compared to 86% at 5 years from diagnosis.

For metastatic cancers (stage 4):

Females aged 50 years and over had lower survival compared to those aged less than 50 years:
- 64% compared to 89% at 1 year from diagnosis;
- 44% compared to 62% at 3 years from diagnosis;
- 28% compared to 48% at 5 years from diagnosis.

Observed survival by stage at diagnosis and remoteness area in 2011

For examination of survival by remoteness area, the data apply to observed rather than relative survival due to an absence of life tables. More information can be found in the ‘About the Data’ tab

For female breast cancers, observed survival by stage at diagnosis was generally similar across remoteness areas for stage 1 to 3 cancers.

For metastatic cancers (stage 4), there tended to be a difference in observed survival between people living in Inner and Outer Regional areas compared to Major Cities at 1 year (65% compared to 69%), 3 years (38% compared to 47%) and 5 years from diagnosis (24% compared to 31%).

For metastatic cancers (stage 4), observed survival was not reported for Remote and Very Remote areas at 1, 3 and 5 years from diagnosis due to small numbers.

Observed survival by stage at diagnosis and socioeconomic status (SES) area in 2011

For examination of survival by SES areas, the data apply to observed rather than relative survival due to an absence of life tables. More information can be found in the ‘About the Data’ tab

For female breast cancers, observed survival was generally similar across SES areas at 1, 3 and 5 years from diagnosis.

For stage 1 cancers, there was a small but significant difference in observed survival between females living in the highest SES areas (SES5, 97%) compared to lower SES areas (SES1-3, between 94 % and 95%) at 5 years from diagnosis.

Observed survival by stage at diagnosis and Indigenous status in 2011

Analyses of survival by stage at diagnosis were not undertaken by Indigenous status due to small numbers.

About the data

The descriptive data in this report are used to describe patterns rather than test hypotheses. For this report, 95% confidence intervals (CIs) are used as a guide to report notable differences in survival. The following approach has been used for reporting these data:

Unless otherwise stated, the patterns described in the text refer to differences where there is no overlap of 95% CIs and which are likely to be non-random differences.
Differences where there is an overlap of 95% CIs are more likely to have occurred by chance. These differences are referred to in the text as ‘generally’ or ‘tended to’ occur. Differences with overlapping CIs should be interpreted with caution.

For analyses by age group, differences in survival between subsequent 5-year age groups (e.g. 45-49 years compared to 50-54 years) were not statistically significant but the overall trend showed a lower survival with increasing age. Data estimates were not provided for some age groups by stage due to small numbers.

Methodology:¹

Relative survival is measure of survival for people diagnosed with cancer compared to survival for the general population. It is defined as a ratio of:

Observed survival (numerator): The proportion of people who are alive following a specified amount of time (e.g. 1 year, 3 years or 5 years) after diagnosis of cancer (observed survival). Observed survival is calculated from population-based cancer data.
Expected survival (denominator): The proportion of people in the general population who are alive over the same time interval (note: of equivalent age and sex to those with the cancer diagnosis). Expected survival is calculated from life tables for the entire Australian population.

For example, if 6 in 10 people with cancer are alive 5 years after their diagnosis (observed survival of 0.6) and 9 in 10 people of equivalent age and sex from the general population are alive after the same 5 years (expected survival of 0.9), then the relative survival of people with cancer would be 0.6 divided 0.9 which equates to 0.67. This means that individuals with cancer are 67% as likely to be alive for 5 years after their diagnosis compared with their counterparts in the general population.

Relative survival for breast cancers by RD-stage at diagnosis was calculated using the cohort method, using the period 2011–2016. In this method, a cohort of patients diagnosed with cancer is followed over time to estimate the proportion surviving for a selected timeframe (for example, 5 years), compared with the general population.³ As estimates of relative survival may vary, confidence intervals are calculated for these estimates to specify a range of values that are likely to contain the true relative survival for the population.

International comparisons of cancer survival should be interpreted with caution due to differences in cancer collection, coding and reporting practices, as well as differences in the methodologies used for calculating survival.¹

Scope:

These data include cases with a principal diagnosis of breast cancer (C50) for which stage data were available. These data exclude:

Male breast cancer cases
Certain morphology codes that were not eligible for staging, such as sarcomas, lymphomas or carcinoid tumours.

RD-stage

RD-stage at diagnosis is defined as the best estimate of summary TNM stage of diagnosis that can be derived by cancer registries from data sources available to them for invasive tumours. These data will be used for statistical purposes as opposed to clinical management. Clinical requirements for prognostic precision differ from epidemiological requirements for comparability and statistical completeness.⁴

Specifically, the collection of RD-stage is intended for epidemiological population-based analyses only – in particular, this information on stage at diagnosis will assist our understanding of the extent of cancer across tumour types and different sociodemographic groups, and associated cancer survival.

The Business Rules used to derive RD-stage have been tested and reviewed by all states and territories to ensure applicability across all Australian population-based cancer registries. The Business Rules have also been endorsed as a national standard for the collection of stage data by the AACR.

Australian Cancer Database⁵

Cancer incidence indicates the number of new cancers diagnosed during a specified time period (usually one year). The major source of national cancer incidence data is the ACD which contains records of all primary, malignant cancers (except basal cell and squamous cell carcinomas of the skin) diagnosed in Australia since 1982.

All Australian states and territories have legislation that makes cancer a notifiable disease. Various designated bodies, i.e., institutions such as hospitals, pathology laboratories and registries of births, deaths and marriages, are required to report cancer cases and deaths to their jurisdictional cancer registries.

Each registry supplies incidence data annually to the AIHW under an agreement between the registries and the AIHW. These data are compiled into the ACD, the only repository of national cancer incidence data.

National Death Index⁶

The National Death Index (NDI) is a database, housed at the AIHW, which contains records of all deaths occurring in Australia since 1980. The data are obtained from the Registrar of Births, Deaths and Marriages in each state and territory. The NDI is designed to facilitate the conduct of epidemiological studies and its use is strictly confined to medical research.

Linkage of RD-stage, the ACD and NDI

The data used for reporting this measure have been created by linkage of data from the RD-stage collection and the ACD. These data are therefore limited to records that have been matched across these two collections. For this analysis, 3.7% records in the RD-stage collection (approximately 2,500 out of 72,200 cases) have been excluded from these analyses for the following reasons:

RD-stage record did not link to the ACD.
The RD-stage record linked to an ACD record that was out of scope.
RD-stage record was ineligible for staging (such as sarcomas, lymphomas or carcinoid tumours).
RD-stage record was a duplicate.

A relatively small number of records (approximately 600, less than 1%) records in the ACD were in scope but did not link to the RD-stage collection. These records did not link because:

They had been altered since being submitted to the ACD and were now out of scope; or
Had been staged at a point after diagnosis but not at diagnosis.

Cancer incidence records from the linked ACD and RD-stage data were linked to the NDI to calculate the survival estimates in this report.

Data caveats:

Data sourced from a linkage of the RD-stage, Australian Cancer Database and National Death Index data collections.
Error bars indicate 95% confidence intervals.
Survival greater than 100% applies where the survival of people with cancer exceeds the survival of people in the general population of equivalent age and sex over an equivalent time period.
‘All stages’ include cases where it was not possible to determine stage at diagnosis (‘unknown’ stage).
This analysis presents relative survival estimates by RD-stage at diagnosis calculated using the cohort method for the period 2011–2016.
Where the relevant life tables were not available (by remoteness area and socioeconomic status area of usual residence), survival estimates are presented for observed survival calculated using the cohort method for the period 2011–2016.
Remoteness areas are classified according to the 2011 Australian Statistical Geography Standard (ASGS) Remoteness Areas. Not all remoteness areas are represented in all jurisdictions. Disaggregation by remoteness area is based on Statistical Area Level 2 (SA2) of usual residence at time of diagnosis.
Socioeconomic groups are classified according to the SEIFA quintile using the Index of Relative Socioeconomic Disadvantage (IRSD). Disaggregation by SEIFA quintile is based on 2011 classifications of Statistical Areas Level 2 (SA2) of usual residence at time of diagnosis.
Analyses by Indigenous status have not been presented due to small numbers.

References

Activity in this area

Cancer Australia, 2008. A National Cancer Data Strategy for Australia. (https://canceraustralia.gov.au/sites/default/files/publications/ncds_final_web1_504af02093a68.pdf).

Cancer Australia. The Stage, Treatment, and Recurrence project. (https://canceraustralia.gov.au/research-data/cancer-data/improving-cancer-data).

Data

Australian Institute of Health and Welfare.

Australian Cancer Incidence and Mortality (ACIM) books provide incidence and mortality by cancer type and selected demographic groups. (https://www.aihw.gov.au/reports/cancer/acim-books/contents/acim-books).

Australian Institute of Health and Welfare.

‘Cancer Data in Australia’ consolidates the ACIM books, Cancer Compendium and summary tables from Cancer in Australia into one product. This was published in December 2018. (https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/summary)

National Cancer Intelligence Network.

The National Cancer Registration and Analysis Service provides information on cancer 1-year relative survival by stage at diagnosis in England.

(http://www.ncin.org.uk/publications/survival_by_stage).

References

1. Australian Institute of Health and Welfare. 2017. Cancer in Australia 2017. Canberra: AIHW.

2. American Joint Committee on Cancer. 2018. Cancer Staging System: AJCC; [cited 2018]. Available from: https://cancerstaging.org/references-tools/Pages/What-is-Cancer-Staging.aspx.

3. Australian Institute of Health and Welfare. 2018. Cancer Data in Australia. Canberra: AIHW. Available from: https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia/contents/summary.

4. Walters S., Maringe C., Butler J., Brierley J. D., Rachet B., Coleman M. P. 2013. Comparability of stage data in cancer registries in six countries: lessons from the International Cancer Benchmarking Partnership. Int J Cancer. 132(3):676-85.

5. Australian Institute of Health and Welfare. 2014. Australian Cancer Database, 2014; Quality Statement Canberra: AIHW [cited 2018]. Available from: http://meteor.aihw.gov.au/content/index.phtml/itemId/687104.

6. Australian Institute of Health and Welfare. 2012. National Death Index; Quality Statement Canberra: AIHW [cited 2018]. Available from: http://meteor.aihw.gov.au/content/index.phtml/itemId/480010.

Summary

Survival remained high for females diagnosed with early stage cancers up to 5 years from diagnosisSurvival for stage 1 cancers overall was 100% at 1, 3 and 5 years from diagnosis. Survival for stage 2 cancers overall was also high at 1 year (100%) and 3 years (98%), but was slightly lower at 5 years (95%) from diagnosis. 

Females diagnosed with advanced cancers had lower relative survival and this progressively decreased in subsequent years from diagnosis Survival for locally advanced cancers (stage 3) overall was high at 1 year (98%), but was lower at 3 years (88%) and 5 years from diagnosis (81%). Survival for metastatic cancers (stage 4) overall was 69% at 1 year, 47% at 3 years and 32% at 5 years from diagnosis.

Females diagnosed with early stage cancers had similar survival across all age groups where data were availableSurvival by age group for stage 1 cancers was at least 98% across all age groups at 1, 3 and 5 years from diagnosis. Survival by age group for stage 2 cancers was similar across all age groups at 1 year (at least 99%), 3 years (between 96% and 99%) and 5 years from diagnosis (between 90% and 97%).

Females diagnosed with advanced cancers had lower survival with increasing ageFor locally advanced cancers (stage 3), survival generally decreased with increasing age for females in age groups between 65 and 85 years and over from 91% to 68% at 3 years from diagnosis; and in age groups between 65 and 84 years from 89% to 67% at 5 years from diagnosis. For metastatic cancers (stage 4), relative survival generally decreased with increasing age for females across all age groups from 95% to 41% at 1 year from diagnosis; and in age groups between 40 and 79 years from 65% to 38% at 3 years from diagnosis.  Relative survival varied among females in age groups between 45 and 74 years, ranging between 30% and 49% at 5 years from diagnosis.

Although there were some differences, observed survival was generally similar by remoteness and socioeconomic status areaFor metastatic cancers (stage 4), observed survival tended to be higher among females living in Major Cities compared to Inner and Outer Regional areas at 1 year (69% compared to 65%), 3 years (47% compared to 38%) and 5 years from diagnosis (31% compared to 24%). For stage 1 cancers, observed survival was slightly higher among females living in the highest SES areas (SES5, 97%) compared to lower SES areas (SES1-3, between 94% and 95%) at 5 years from diagnosis.

Analyses by Indigenous status were not possible due to small numbers

Revision Type

Major

Version Number

1.0.0

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Data

Relative survival by RD-stage at diagnosis for female breast cancers diagnosed in 2011

Relative survival by stage at diagnosis and age in 2011

Observed survival by stage at diagnosis and remoteness area in 2011

Observed survival by stage at diagnosis and socioeconomic status (SES) area in 2011

Observed survival by stage at diagnosis and Indigenous status in 2011

Summary

Survival remained high for females diagnosed with early stage cancers up to 5 years from diagnosis

Females diagnosed with advanced cancers had lower relative survival and this progressively decreased in subsequent years from diagnosis

Females diagnosed with early stage cancers had similar survival across all age groups where data were available

Females diagnosed with advanced cancers had lower survival with increasing age

Although there were some differences, observed survival was generally similar by remoteness and socioeconomic status area

Analyses by Indigenous status were not possible due to small numbers